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Analysis of institutional authors

Ciocia, AAuthorMestre-Farras, NAuthorVicent-Nacht, IAuthorGuitart, TAuthorGebauer, FCorresponding Author

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April 18, 2024
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Article
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CSDE1: a versatile regulator of gene expression in cancer

Publicated to: Nar Cancer. 6 (2): zcae014- - 2024-04-08 6(2), DOI: 10.1093/narcan/zcae014

Authors:

Ciocia, Annagiulia; Mestre-Farras, Neus; Vicent-Nacht, Ignacio; Guitart, Tanit; Gebauer, Fatima
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Affiliations

Barcelona Inst Sci & Technol, Ctr Genom Regulat CRG, Dr Aiguader 88 - Author
Univ Pompeu Fabra UPF, Dr Aiguader 88 - Author

Abstract

RNA-binding proteins (RBPs) have garnered significant attention in the field of cancer due to their ability to modulate diverse tumor traits. Once considered untargetable, RBPs have sparked renewed interest in drug development, particularly in the context of RNA-binding modulators of translation. This review focuses on one such modulator, the protein CSDE1, and its pivotal role in regulating cancer hallmarks. We discuss context-specific functions of CSDE1 in tumor development, its mechanisms of action, and highlight features that support its role as a molecular adaptor. Additionally, we discuss the regulation of CSDE1 itself and its potential value as biomarker and therapeutic target. Graphical Abstract
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Keywords

DifferentiationInitiationPoly(a)-binding proteinRibosome entry segmentRna-binding proteinsRolesTranslationTurnoverUnrUpstream

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal NAR Cancer due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Oncology.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • WoS: 3
  • Europe PMC: 3
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 8.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 8 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 5.
  • The number of mentions on the social network X (formerly Twitter): 5 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (CIOCIA, ANNAGIULIA) and Last Author (GEBAUER HERNÁNDEZ, FÁTIMA).

the author responsible for correspondence tasks has been GEBAUER HERNÁNDEZ, FÁTIMA.

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